| Name | Pos | Salary | Through | Years Left | Note | Years in Majors |
| V. Guerrero | RF | $6,290,000 | 2010 | 4 years left | | 11 years |
| D. Wright | 3B | $5,900,000 | 2007 | 1 years left | Arbitration (Estimate: $3,660,000) | 3 years |
| J. Lackey | SP | $4,042,857 | 2007 | 1 years left | Free agent after this season! | 5 years |
| C. Lee | LF | $3,390,000 | 2007 | 1 years left | Free agent after this season! | 8 years |
| C. Zambrano | SP | $3,000,000 | 2011 | 5 years left | | 6 years |
| M. Timlin | MR | $2,020,000 | 2011 | 5 years left | | 16 years |
| D. Matsuzaka | SP | $1,471,429 | 2007 | 1 years left | Arbitration (Estimate: $1,280,000) | 1 years |
| O. Cabrera | SS | $930,000 | 2011 | 5 years left | | 10 years |
| J. Varitek | C | $820,000 | 2007 | 1 years left | Free agent after this season! | 10 years |
| K. Youkilis | 1B | $635,714 | 2007 | 1 years left | Arbitration (Estimate: $550,000) | 3 years |
| J. Hardy | SS | $600,000 | 2007 | 1 years left | Arbitration (Estimate: $520,000) | 2 years |
| R. Hernandez | C | $530,000 | 2010 | 4 years left | | 8 years |
| J. Moyer | SP | $490,000 | 2011 | 5 years left | | 20 years |
| J. Gathright | LF | $392,857 | 2007 | 1 years left | Arbitration (Estimate: $340,000) | 3 years |
| R. Gotay | 2B | $371,429 | 2007 | 1 years left | Arbitration (Estimate: $320,000) | 2 years |
| T. Hafner | 1B | $300,000 | 2007 | 1 years left | Free agent after this season! | 5 years |
| E. Gagne | MR | $300,000 | 2007 | 1 years left | Free agent after this season! | 8 years |
| A. Embree | MR | $300,000 | 2007 | 1 years left | Free agent after this season! | 13 years |
| H. Bailey | SP | $300,000 | 2007 | 1 years left | Automatic Resign. | 1 years |
| J. Pierre | CF | $300,000 | 2007 | 1 years left | Free agent after this season! | 7 years |
| J. Votto | 1B | $300,000 | 2007 | 1 years left | Automatic Resign. | 1 years |
| A. Jones | CF | $300,000 | 2007 | 1 years left | Free agent after this season! | 11 years |
| Y. Molina | C | $300,000 | 2007 | 1 years left | Arbitration (Estimate: $300,000) | 3 years |
| V. Diaz | RF | $300,000 | 2007 | 1 years left | Arbitration (Estimate: $300,000) | 3 years |
| L. Gardner | MR | $300,000 | 2007 | 1 years left | Arbitration (Estimate: $1,600,000) | 2 years |
| J. Broxton | CL | $300,000 | 2007 | 1 years left | Arbitration (Estimate: $1,690,000) | 2 years |
| C. Schilling | SP | $300,000 | 2007 | 1 years left | Free agent after this season! | 19 years |
| J. Borowski | CL | $300,000 | 2007 | 1 years left | Free agent after this season! | 10 years |
| M. Cuddyer | RF | $300,000 | 2007 | 1 years left | Free agent after this season! | 6 years |
| A. Brown | MR | $300,000 | 2007 | 1 years left | Automatic Resign. | 1 years |
| B. Arroyo | MR | $300,000 | 2007 | 1 years left | Free agent after this season! | 7 years |
| F. Morales | SP | $300,000 | 2007 | 1 years left | Automatic Resign. | 1 years |
| J. Fogg | MR | $300,000 | 2007 | 1 years left | Free agent after this season! | 6 years |
| D. Sarfate | MR | $300,000 | 2007 | 1 years left | Automatic Resign. | 1 years |
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